is approved by consumers

Testimonials based on real consumers’ feedbacks. Available upon request.

1 – Satisfaction reported during a survey performed on 1.161 volunteers. Taban J. Soigner le patient colopathe, La revue Pharma. 2015 October,125:44




of consumer satisfaction1

Consumers also reported a fast-acting gastrointestinal comfort with ibsium
(learn more)

A high level of science

Saccharomyces cerevisiae
CNCM I-3856

Saccharomyces cerevisiae CNCM I-3856
benefits from:

  • Studies on more than 1700 volunteers including 600 during clinical studies
  • The guarantee of recognized and independent experts in digestive diseases
  • A meta-analysis confirming our robust science and strenghtening our conclusions.

Saccharomyces cerevisiae CNCM I-3856
may help alleviate occasional:

  • Intestinal pain
  • Bloating
  • Constipation

*IBS = Irritable Bowel Syndrome
** IBD = Inflammatory Bowel Disease
*** Efficacy of probiotics is considered by the scientific community as similar when dosage remains within the same log

natural origin

Ingredient of natural origin

ibSium® is a live healthy yeast of natural origin.

ibSium® is the brand name of Saccharomyces cerevisiae CNCM I-3856, an exclusive yeast strain patented by Lesaffre. This innovative ingredient is used in a wide range of dietary supplements developed by our partners since 2010.


Discovered in Lesaffre’s laboratories, ibSium® has been selected by our experts among our collection of thousands of strains for its superior capacity to help alleviating intestinal occasional disorders.

Regulatory & Intellectual property requirements vary by country and applications (including claims). We encourage our customers to consult their legal department or counsel before launching the product on the market.


Your safe intestinal ally that fits all diets

ibSium® IS SAFE

  • ibSium® is a safe solution that helps thousands of people all over the world each year.
  • It can be consumed without side effects or developing habituation.
  • The safety of ibSium® is also in compliance with authorities’ guidelines (EU Qualified Presumption of Safety & US Generally Recognized As Safe – 21 CFR)


  • ibSium® can be consumed by people with special diets.

IbSium natural solutions


Consumers report rapid efficiency

77% of people



of consumers experienced ibSium®
effects within the first 15 days of consumption.

Consumers also reported 96% satisfaction with ibSium®.
(learn more)

fast acting

Satisfaction reported during a survey performed on 1161 volunteers. Taban J. Soigner le patient colopathe, La revue Pharma. 2015 October, 125: 44
Unpublished data. Data available upon request.


survives through the digestive tract

Survival through the human gastrointestinal (GI) tract is a challenge for microorganisms, such as live healthy yeasts: they are indeed exposed to sequential stresses during digestion affecting their viability and activity.


ibSium® has been shown to survive through the digestive tract and can therefore reach the gut where it may help to support digestive health.

ibSium® benefits from a natural encapsulation contributing to the survival through the digestive tract and allowing stability in various finished products.

Cordonnier C, Thévenot J, Etienne-Mesmin L, Denis S, Alric M, Livrelli V and Blanquet-Diot S. Dynamic In Vitro Models of the Human Gastrointestinal Tract as Relevant Tools to Assess the Survival of Probiotic Strains and Their Interactions with Gut Microbiota. Microorganisms, 2015, 3(4):725-745


About us

ibSium®: backing up on Lesaffre’s experience

Innovative global player in yeast, bacteria and pure molecule from fermentation, Gnosis by Lesaffre provides scientifically-proven and sustainably-sourced active ingredients and solutions to customers in the pharmaceutical, nutritional and functional food industries for a wide range of health benefits.


Learn more about us

Gnosis by Lesaffre is a business unit of Lesaffre.

Contact us

ibSium® is your daily ally to help support intestinal comfort and preserve your quality of life

Contact us to learn more about ibSium®.

  • Ce champ n’est utilisé qu’à des fins de validation et devrait rester inchangé.